FROM SYSTEM MODELING TO SYSTEM ANALYSIS: THE IMPACT OF RESOLUTION LEVEL AND RESOLUTION DISTRIBUTION IN THE COMPUTER-AIDED INVESTIGATION OF BIOMOLECULES

The ever increasing computer power, together with the improved accuracy of atomistic force fields, enables researchers to investigate biological systems at the molecular level with remarkable detail.However, the relevant length and time scales of many processes of interest are still hardly within reach even for state-of-the-art hardware, thus leavi

Abstract Schizophrenia, as one of the most common disorders from the psychotic spectrum is most commonly detected in the phase of first psychosis and may pose a diagnostic challenge, as commonly comprise a heterogeneous group of schizophrenias, with distinct clinical presentations.If it detected in its prodromal phase without clearly developed psyc

The South-to-North Water Diversion Project (SNWDP) is a megaproject which has been constructed to alleviate imbalanced water resource distribution between northern and southern China.It encompasses three routes distributed in the east, central, and west of China, respectively.The central route (CR) of the SNWDP starts from the Danjiangkou Reservoir

Abstract Background Cystic Fibrosis Related Diabetes (CFRD) is a frequent comorbidity of patients with Cystic Fibrosis (CF).A worsening of clinical conditions appears before CFRD.It has been demonstrated a decline in pulmonary function and nutritional status also in patients with prediabetes.Few trials show that insulin may be beneficial in prediab